“Biotics to promote a healthy dietary intake” – BITASAL. AVI, Agencia Valenciana de la Innovación. European Regional Development Fund Programme (ERDF) Comunitat Valenciana 2021-2027. Ref: INNVA1/2023/24. 2023- 2025. Principal Investigator: Prof. Yolanda Sanz.
The main objective of this project is the valorisation of a human intestinal bacterium to regulate alterations in eating behaviour and promote healthy eating habits.
Objectives
• Optimise sustainable production of the bacterium and postbiotic
• Validate preclinical efficacy of the postbiotic compared to the probiotic
• Confirming the stability and biological activity during gastrointestinal transit
Strategy
• Optimisation of bacterial production
• Validation of the functional equivalence of the live and dead bacterium
• Evaluating the stability of the postbiotic during human intestinal transit
• Production of the postbiotic for studies
• Demonstration of in vivo functionality of the final postbiotic product
• Identification of functional genes and molecules of the pro- and postbiotic
Impact
• Preventing and reducing eating disorders (excessive food intake)