This week has been published in the scientific journal Best Practice & Research: Clinical Endocrinology & Metabolism a review article entitled: ‘The gut microbiota as a versatile immunomodulator in obesity and associated metabolic disorders‘, whose authors are our colleagues Rebeca Liébana-García, Marta Olivares, Clara Bullich-Vilarrubias, Inmaculada López-Almela, Marina Romaní-Perez and Yolanda Sanz, belonging to the Microbial Ecology, Nutrition and Health Research Unit of the IATA-CSIC.
Attached is a short preview of this interesting article:
“Obesity is reaching epidemic proportions and currently represents a major public health challenge. The high prevalence is explained by the intake of energy-rich diets, coupled with a sedentary lifestyle. In addition to these two factors, the gut microbiome has recently been proposed as a new biological factor involved in the development of obesity. In this sense, the gut microbiome acts as a synergistic force that can either protect or aggravate the effects of diet. In part, the influence of the microbiome on this response to diet, and thus on the development of obesity, occurs through the regulation of intestinal and systemic immunity. In this article, we review the mechanisms by which obesogenic diets and the microbiome affect immunity, focusing on the consequences of this dialogue on the gut-adipose tissue axis. We also review the metabolites and structural compounds of certain gut bacteria that influence metabolism through the immune system. Finally, we explore how advances in this field of research could help design microbiome-based strategies to more effectively address metabolic disorders.”
Being published under the Open Science (CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/) the article is publicly available to read or download via the following link (.pdf file):
‘The gut microbiota as a versatile immunomodulator in obesity and associated metabolic disorders‘
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