The review article ‘Gut microbiome and anti-viral immunity in COVID-19‘ (doi: 10.1080/10408398.2022.2143476) has recently been published in Critical Reviews in Food Science and Nutrition. Its authors are Valerio Rossini, Veronica Tolosa-Enguis, Carlos Frances-Cuesta and Yolanda Sanz from the Microbiome, Nutrition and Health Research Unit at IATA-CSIC.
Here is a brief summary of its contents:
“SARS-CoV-2 mainly affects the respiratory system, but the gastrointestinal tract is also a target. Prolonged disorders, in COVID-19 patients, were correlated with decreased richness and diversity of the gut microbiota, immune deregulation and delayed viral clearance. Although there are no definitive conclusions, ample evidence would suggest that the gut microbiome composition and function play a role in COVID-19 severity, progression and persistence.
Microbiome based strategies for population stratification and COVID-19 infection management are under investigation, representing an area of interest in the pandemic. In this review, we present the existing data related to the interaction between gut microbes and the host’s immune response to SARS-CoV-2 and discuss the implications for current disease management and readiness to face future pandemics.”