Innobiome – Microbioma e Innovación

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So far Innobiome has created 57 blog entries.

Publication of original article: “Bacteroides uniformis CECT 7771 requires adaptive immunity to improve glucose tolerance but not to prevent body weight gain in diet-induced obese mice” in scientific journal Microbiome

By Innobiome|2024-07-31T12:49:25+02:0031/07/2024|Tags: bacteroides uniformis, gut microbiota, intestinal immunity, obesity, oral glucose intolerance|

The original article ‘‘Bacteroides uniformis CECT 7771 requires adaptive immunity to improve glucose tolerance but not to prevent body weight gain in diet-induced obese mice” (doi: 10.1186/s40168-024-01810-3.) has recently been published in Microbiome. Its authors are Marina Romaní-Pérez, Inmaculada López-Almela, Clara Bullich-Vilarrubias, Zoran Evtoski, Alfonso Benítez-Páez and Yolanda Sanz. Here is a brief summary of its contents: “The metabolic disturbances of obesity can be mitigated by strategies modulating the gut microbiota. In this study, we sought to identify whether innate Leer más

Yolanda Sanz participates in the report on “Metabolic Diseases: the epidemics of the 21st Century” of the CSIC Science4Policy project

By Innobiome|2024-02-16T13:07:38+02:0016/02/2024|Tags: gut microbiome, metabolic diseases, science4 policy, yolanda sanz|

The Consejo Superior de Investigaciones Científicas (CSIC) has announced the selection of the proposal "Metabolic Diseases: the epidemics of the 21st Century” as an outstanding contribution to the Science4Policy project. Dr. Yolanda Sanz, Research Professor of the Microbiome, Nutrition and Health Group at the Institute of Agrochemistry and Food Technology (IATA), will participate in the drafting of a Science for Public Policy report on this type of Pathologies. The Science4Policy collection has 6 reports on topics of current concern to Leer más

Publication of `News & Views´ Nature article “Turning cooperative bacteria into probiotics for human health”

By Innobiome|2023-09-25T09:12:05+02:0025/09/2023|Tags: anaerobic intestinal bacteria, probiotics|

Yolanda Sanz has contributed to the News & Views section of Nature with the publication of the article 'Turning cooperative bacteria into probiotics for human health ' (doi: 10.1038/d41586-023-02407-w). This contribution discusses the challenges of developing a next-generation of probiotics formed by anaerobic intestinal bacteria, which interact with each other and with the human body, providing health benefits. This paper reviews the one recently published by Khan et al (doi: 10.1038/s41586-023-06378-w) where they study a combination of two intestinal bacteria Leer más

Publication of review article “Tracking microbiota fibre breakdown to treat NASH”

By Innobiome|2023-07-28T08:55:23+02:0028/07/2023|Tags: intestinal microbiota, inulin, liver cirrhosis, NASH, non-alcoholic steatohepatitis|

The review article 'Tracking microbiota fibre breakdown to treat NASH' (doi: 10.1038/s41564-023-01440-9) has recently been published in the journal Nature Microbiology. Its authors are Alejandra Flor, Marta Olivares and Yolanda Sanz from the Microbiome, Nutrition and Health unit at IATA-CSIC. The article evaluates how the interaction between the intestinal microbiota of mice and inulin, a soluble dietary fibre naturally present in foods such as artichokes, asparagus, onions and leeks, generates a compound that helps to alleviate non-alcoholic steatohepatitis (NASH), a Leer más

Publication of review article “Gut microbiome and anti-viral immunity in COVID-19”

By Innobiome|2023-05-03T09:39:39+02:0003/05/2023|Tags: covid-19, human microbiome, intestinal microbiota, microbiota|

The review article ‘Gut microbiome and anti-viral immunity in COVID-19‘ (doi: 10.1080/10408398.2022.2143476) has recently been published in Critical Reviews in Food Science and Nutrition. Its authors are Valerio Rossini, Veronica Tolosa-Enguis, Carlos Frances-Cuesta and Yolanda Sanz from the Microbiome, Nutrition and Health Research Unit at IATA-CSIC. Here is a brief summary of its contents: “SARS-CoV-2 mainly affects the respiratory system, but the gastrointestinal tract is also a target. Prolonged disorders, in COVID-19 patients, were correlated with decreased richness and diversity Leer más

THDMI The Human Diet & Microbiome Initiative

By Innobiome|2022-09-20T11:33:16+02:0020/09/2022|Tags: diet, gut, lifestyle, microbiome, thdmi|

“The Human Diets & Microbiome Initiative” (THDMI) aims at understanding the influence of different diets and lifestyles on our gut microbiome. To this end, this link is being investigated in different geographic regions and has already been done in the US, the UK, and Mexico. This year the initiative reaches Spain with the collaboration of the research group of Yolanda Sanz at IATA-CSIC (Spanish National Research Council) in Valencia. This study is under the umbrella of a global microbiome action Leer más

The project “Optimization and validation of the production of new generation probiotics for obesity” reaches its end with very promising results.

By Innobiome|2021-12-14T13:44:57+02:0014/12/2021|Tags: AVI2020, microencapsulation, obesity, P.faecium, probiotic, yolandasanz|

The project "Optimization and validation of the production of new generation probiotics for obesity" of two years, awarded in 2020 by the Valencian Agency of Innovation (AVI) to the research group of Prof. Yolanda Sanz reaches its end with great results. This project focused on an intestinal bacterium with preclinical effectiveness against obesity, Phascolarctobacterium faecium (P. faecium) and had three main objectives: 1) To demonstrate that the bacterium is safe for consumption. 2) To optimize the production and scale-up of Leer más

Publication of original article: “Holdemanella biformis improves glucose tolerance and regulates GLP-1 signaling in obese mice” in scientific journal The FASEB Journal

By Innobiome|2021-08-31T10:43:29+02:0008/09/2021|Tags: glucose tolerance, holdemanella biformis, obesity, type 2 diabetes, yolanda sanz|

The original article 'Holdemanella biformis improves glucose tolerance and regulates GLP-1 signaling in obese mice' (doi: 10.1096/fj.202100126R) has recently been published in the FASEB Journal. Its authors are Marina Romaní-Pérez, Inmaculada López-Almela, Clara Bullich-Vilarrubias, Lola Rueda-Ruzafa, Eva M Gómez Del Pulgar, Alfonso Benítez-Páez, Gerhard Liebisch, José Antonio Lamas and Yolanda Sanz Yolanda Sanz. This work is the result of collaboration between the Microbial Ecology, Nutrition and Health unit of the IATA-CSIC, the Neuroscience group of the CINBIO (University of Vigo) Leer más

Publication of review article “The Microbiota and the Gut-brain axis in controlling food intake and energy homeostasis”

By Innobiome|2021-08-31T10:46:51+02:0003/09/2021|Tags: energy homeostasis, food intake, gut brain axis, obesity|

The review article 'The Microbiota and the Gut-brain axis in controlling food intake and energy homeostasis' (doi: 10.3390/ijms22115830) has recently been published in the International Journal of Molecular Science, included in the special issue on Hypothalamic regulation of obesity. Its authors are Marina Romaní-Pérez, Clara Bullich-Vilarrubias, Inmaculada López-Almela, Rebeca Liébana-García, Marta Olivares and Yolanda Sanz from the Microbial Ecology, Nutrition and Health unit of the IATA-CSIC. Here is a brief summary of its contents: "Obesity currently represents a major societal Leer más

NutriLecturas: What do we know about coeliac disease?

By Innobiome|2021-08-06T11:42:53+02:0011/08/2021|Tags: intestinal microbiota, NutriLecturas, nutrition|

On Thursday, 20th May, our colleague Marta Olivares participated in the reading club "NutriLecturas" coordinated by Dr. Jara Pérez from ICTAN-CSIC. "NutriLecturas" is an initiative supported by the FECYT and aims to promote open scientific reading clubs in research centers. Through her participation in this initiative, Marta Olivares discussed different nutrition and intestinal microbiota aspects with the reading club participants. The discussion was related to the outreach book “What do we know about coeliac disease?" (Editorial Catarata). The session was Leer más

International Human Microbiome Consortium Congress, Barcelona 2021

By Innobiome|2021-08-06T11:12:28+02:0006/08/2021|Tags: chronic social stress, diabetes, IHMC, microbiota, obesity|

This past June, on 27, 28 and 29, three of the PhD students attended virtually the 8th International Human Microbiome Consortium Congress 2021 (IHMC), in order to present the advances in their respective research topics, and above all to continue learning from other fellow researchers. Clara Bullich made her debut with an oral presentation on a specific strain of Holdemanella biformis, an intestinal bacterium isolated in Prof. Yolanda Sanz's laboratory. The potential of this bacterium as a "new generation" probiotic Leer más

A probiotic to prevent and treat obesity and its cormobilities

By Innobiome|2021-05-21T10:16:35+02:0021/05/2021|Tags: innobiome, intestinal microbiota investigation, microbiome, microbiota, nutrition, obesity, probiotics, videos|

As you can read in the article published by CSIC (read article), our research group at IATA-CSIC, led by Prof. Yolanda Sanz, has developed a probiotic that prevents and treats obesity and its associated diseases (cormobilities). The project to advance in future commercialization is funded by the Agència Valenciana de la Innovació (AVI) and is being carried out in collaboration with the Instituto Tecnológico de la Industria Agroalimentaria (AINIA). We show you a short video explaining the project:

Annual meeting of the Consortium of the European project CIRCLES

By Innobiome|2021-05-18T15:44:27+02:0018/05/2021|Tags: circles, european projects, health, innobiome, intestinal microbiota investigation, microbiome, microbiota, nutrition, research food systems|

On 27 April our IATA-CSIC research group attended the annual consortium meeting of the European project CIRCLES: Control of microbiome circulation to improve food systems, part of the Horizon 2020 Programme of the European Union. Due to the current situation caused by the COVID-19 pandemic, this year the meeting was held in an online format. Under this exceptional situation, and after 30 months of research and work, an extension of 1 year has been granted to continue working on this Leer más

Publication of the article ‘The gut microbiota as a versatile immunomodulator in obesity and associated metabolic disorders’

By Innobiome|2021-05-14T10:59:05+02:0014/05/2021|Tags: gut microbiota, inmunidad innata, innate inmunity, innobiome, metabolic health, microbiome, obesity, publicaciones, salud metabolica, sistema inmunitario|

This week has been published in the scientific journal Best Practice & Research: Clinical Endocrinology & Metabolism a review article entitled: 'The gut microbiota as a versatile immunomodulator in obesity and associated metabolic disorders', whose authors are our colleagues Rebeca Liébana-García, Marta Olivares, Clara Bullich-Vilarrubias, Inmaculada López-Almela, Marina Romaní-Perez and Yolanda Sanz, belonging to the Microbial Ecology, Nutrition and Health Research Unit of the IATA-CSIC. Attached is a short preview of this interesting article: "Obesity is reaching epidemic proportions and Leer más

Publication of Volume 4 of the CSIC White Paper: ‘Challenges in Biomedicine & Health’

By Innobiome|2021-05-08T17:06:08+02:0010/05/2021|Tags: biomedicine, csic, csic white paper, health, white paper csic|

The volume 4 of the CSIC White Paper, entitled 'Challenges in Biomedicine & Health', although still in the process of being published on paper, has recently been published in electronic format (ebook) and can now be downloaded free of charge from this link. Mario Delgado, coordinator of the project together with María Moros, expressed his gratitude for the effort and dedication of all the people involved in this volume 4 of the CSIC White Paper. About the book Title: Challenges Leer más

Learn more about the importance of the microbiome in our health by taking the MOOC ‘The Human Microbiome’

By Innobiome|2021-05-07T09:19:28+02:0007/05/2021|Tags: eit food, health, human microbiome course, microbiome, microbiome courses, nutrition, the human microbiome|

In the context of a European initiative 'EIT-FOOD', our research group, and especially Marta Olivares and Rebeca Liébana, have participated in the development of a MOOC (Massive On-line Open Course) together with collaborators from the University of Turin (Italy), Microbion (Italy), Quadram institute (UK) and the University of Reading (UK). The course, entitled 'The Human Microbiome', lasts three weeks and is available for free on the FutureLearn platform until 30 November 2021. In this course you will learn how a Leer más

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